发明名称 MODULATION OF GLUCOCORTICOID RECEPTOR EXPRESSION
摘要 Compounds, compositions and methods are provided for modulating the expression of glucocorticoid receptor. The compositions comprise antisense compounds, particularly antisense oligonucleotides which have particular in vivo properties, targeted to nucleic acids encoding glucocorticoid receptor. Methods of using these compounds for modulation of glucocorticoid receptor expression and for treatment of diseases are provided.
申请公布号 US2010222412(A1) 申请公布日期 2010.09.02
申请号 US20100687533 申请日期 2010.01.14
申请人 ISIS PHARMACEUTICALS, INC. 发明人 MONIA BRETT P.;MCKAY ROBERT;FREIER SUSAN M.;BHANOT SANJAY;WATTS LYNNETTA
分类号 A61K31/7088;A61P3/00;A61P3/04;A61P7/12;C07H21/04;C12N5/02;C12N15/113 主分类号 A61K31/7088
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