Pellets Comprising a Core With a Water-Soluble Carrier

摘要

A pellet with a length/width ratio of less than about 1.4 is provided which comprises a core which comprises a water-soluble carrier and an active ingredient distributed homogeneously therein. The pellet disintegrates, with visually ascertainable loss of the pellet structure, into smaller fragments when the following test is carried out: (a) 200 to 800 mg of pellets are placed into a Petri dish with 0.5 ml of demineralized water. (b) The Petri dish is immediately afterwards fixed to the measuring cylinder holder of a stamping volumeter. (c) After 10 seconds, 30 stamping movements are carried out. (d) Immediately afterwards, the pellets are photographed.