发明名称 COMPOSITIONS AND METHODS FOR ENHANCING NEUROPROTECTION VIA ADMINISTRATION OF STEM CELLS AND BLOOD BRAIN BARRIER PERMEABILIZERS
摘要 The present invention provides compositions and methods for enhancing the neuroprotective effect of umbilical cord blood cells. More particularly, the present invention provides methods of treating neurodegenerative disorders by administering umbilical cord blood cells and a substance capable of permeabilizing the blood brain barrier. In one embodiment, the blood brain barrier permeabilizer is mannitol. In another embodiment, the blood brain barrier permeabilizer is Cereport.
申请公布号 US2010221233(A1) 申请公布日期 2010.09.02
申请号 US20100719565 申请日期 2010.03.08
申请人 UNIVERSITY OF SOUTH FLORIDA 发明人 BORLONGAN CESARIO V.;SANBERG PAUL R.
分类号 A61K35/14;A61K35/44;A61P9/00;A61P25/16;A61P25/28 主分类号 A61K35/14
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