发明名称 |
NON SEPARATION ASSAYS WITH SELECTIVE SIGNAL INHIBITORS |
摘要 |
Methods, reagents, kits and systems are disclosed for determining an analyte in a sample, the assay method comprising forming a reaction mixture in an aqueous solution, by adding a chemiluminescent-labeled immobilized specific binding member, an activator-labeled specific binding member, a selective signal inhibiting agent, and a sample, wherein the chemiluminescent-labeled immobilized specific binding member and activator-labeled specific binding member bind to analyte present in the sample to form a binding complex, and adding to the reaction mixture a trigger solution to release a detectable chemiluminescent signal correlated to the amount of the analyte-bound binding complex present in the reaction mixture.
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申请公布号 |
CA2753596(A1) |
申请公布日期 |
2010.09.02 |
申请号 |
CA20102753596 |
申请日期 |
2010.02.26 |
申请人 |
BECKMAN COULTER, INC. |
发明人 |
AKHAVAN-TAFTI, HASHEM;DE SILVA, RENUKA;MCLERNON, TERRI;MENDOZA, JAMES;SALVATI, MICHAEL;SHAPIR, NIR;XIE, WENHUA |
分类号 |
C12Q1/28;G01N33/542;G01N33/58 |
主分类号 |
C12Q1/28 |
代理机构 |
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