发明名称 |
Synthesis of sialic acid in plants |
摘要 |
A method of synthesizing sialic acid in plants, and plants capable of synthesizing sialic acid is provided. Furthermore, a method of producing sialylated protein in a plant is also provided. The method to synthesize sialic acid comprises providing a plant comprising a nucleotide sequence encoding N-acetyl neuraminic acid (Neu5Ac) synthase or Neu5Ac lyase, and expressing the nucleotide sequence thereby synthesizing sialic acid. The plant may also co-express a nucleotide sequence encoding one or more than one of an epimerase, a CMP-Neu5Ac synthase, a CMP-Neu5Ac transporter and a sialyltransferase. |
申请公布号 |
EP2224009(A1) |
申请公布日期 |
2010.09.01 |
申请号 |
EP20100166705 |
申请日期 |
2007.02.09 |
申请人 |
MEDICAGO INC.;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE;UNIVERSITE DE ROUEN |
发明人 |
PACCALET, THOMAS;BARDOR, MURIEL;RIHOUEY, CHRISTOPHE;GOMORD, VERONIQUE;FAYE, LOIC;LEROUGE, PATRICE;AQUIN, STEPHANIE;VEZINA, LOUIS-PHILIPPE;D'AOUST, MARC-ANDRE |
分类号 |
C12N15/82;A01H5/00;A01H5/10;C12N5/04;C12N5/10;C12N9/88;C12N9/90;C12N15/54;C12N15/60;C12P19/26;C12P21/00 |
主分类号 |
C12N15/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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