发明名称 METHODS FOR DETECTING LUNG CANCER AND MONITORING TREATMENT RESPONSE
摘要 <p>A method is described for detecting lung cancer comprising detecting an elevated level of a CTAP III-related biomarker in a biological sample from a subject at risk for developing lung cancer. Further, a method is described for predicting risk of developing lung cancer in a subject comprising detecting an elevated level of a CTAP III-related biomarker in a biological sample from a subject. Additionally, a method of monitoring the success of lung cancer treatment is described comprising detecting levels of a CTAP III-related biomarker in a biological sample from a subject undergoing treatment for lung cancer for comparison with a previous level obtained from the subject. Multivariate analysis may be incorporated into these methods, evaluating such clinical, or demographic risk factors as age, sex, smoking history, smoking status, smoking family history, education level, COPD, socio-economic status, body mass index and lung function. Kits for conducting such methods are described.</p>
申请公布号 EP2222345(A1) 申请公布日期 2010.09.01
申请号 EP20080852226 申请日期 2008.11.24
申请人 BRITISH COLUMBIA CANCER AGENCY BRANCH 发明人 LAM, STEPHEN;YEE, JOHN;KUZYK, MICHAEL;SIN, DON;SADAR, MARIANNE, DOROTHY;TAMMEMAGI, CARL, MARTIN
分类号 G01N33/574;A61K49/00;G01N33/68;G01N33/72 主分类号 G01N33/574
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