THE MUTANT OF SACCHAROMYCES CEREVISIAE PRODUCING GLUTATHIONE TO HIGH CONCENTRATIONS AND THE MASS PRODUCTION METHOD OF GLUTATHIONE BY CULTURING THE MUTANT OF SACCHAROMYCES CEREVISIAE

摘要

PURPOSE: A mutant of Saccharomyces cerevisiae which produces glutathione of high concentration is provided to massively produce glutathione and to improve productivity. CONSTITUTION: A mutant of Saccharomyces cerevisiae, yeast 54-8m(KACC 93070P) is able to overexpress glutathione. The mutant is prepared by irradiating UV in a distance of 25-35cm for 10-60 minutes. A method for culturing mutant of Saccharomyces cerevisiae for overexpressing glutathione comprises: a step of preparing mutant of Saccharomyces cerevisiae; a step of the mutant in a culture medium at 30-35°C, pH 5.5-6.5 for 1-2 days.