发明名称 |
NUCLEOTIDE SEQUENCES THAT ENCODE DEREGULATED PHOSPHOGLYCERATE DEHYDROGENASES OF CORYNEFORM BACTERIA AND METHOD FOR PRODUCING L-SERINE |
摘要 |
The invention relates to nucleotide sequences of coryneform bacteria that encode proteins that are involved in the biosynthesis of L-serine and to a method for producing L-serine. According to the invention, at least 79 amino acids at the C terminus of the wild-type serA sequence are deleted, thereby producing a 3-phosphoglycerate dehydrogenase having a reduced feedback inhibition by L-serine vis-à-vis the wild-type sequence. |
申请公布号 |
EP1520013(B1) |
申请公布日期 |
2010.09.01 |
申请号 |
EP20030763598 |
申请日期 |
2003.07.08 |
申请人 |
FORSCHUNGSZENTRUM JUELICH GMBH;AMINO GMBH |
发明人 |
EGGELING, LOTHAR;PETERS-WENDISCH, PETRA;NETZER, ROMAN;SAHM, HERMANN;FAURIE, ROBERT;KLASSEN, BIRGIT |
分类号 |
C12N9/04;C12N15/53;C12N15/63;C12P13/06 |
主分类号 |
C12N9/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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