发明名称 Tetrahydropyranyl cyclopentyl tetrahydropyridopyridine modulators of chemokine receptor activity
摘要 The present invention is directed to compounds of the formula I: (wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, n and the dashed line are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptor CCR-2. The present invention is also directed to intermediates useful in the preparation of formula I compounds.
申请公布号 US7786305(B2) 申请公布日期 2010.08.31
申请号 US20040856012 申请日期 2004.05.28
申请人 MERCK SHARP & DOHME CORP. 发明人 JIAO RICHARD;MORRIELLO GREGORI;YANG LIHU;ZHOU CHANGYOU;KOTHANDARAMAN SHANKARAN;MOYES CHRISTOPHER
分类号 C07D213/00;C07D471/04;A61P29/00;C07C61/06;C07C61/20;C07C62/08;C07C62/34;C07C261/00;C07C269/00;C07C271/00;C07D;C07D207/30 主分类号 C07D213/00
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