| 发明名称 |
Polypeptide variants with altered effector function |
| 摘要 |
The present invention concerns polypeptides comprising a variant Fc region. More particularly, the present invention concerns Fc region-containing polypeptides that have altered effector function as a consequence of one or more amino acid modifications in the Fc region thereof.
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| 申请公布号 |
US7785791(B2) |
申请公布日期 |
2010.08.31 |
| 申请号 |
US20080033642 |
申请日期 |
2008.02.19 |
| 申请人 |
GENENTECH, INC. |
发明人 |
PRESTA LEONARD |
| 分类号 |
C12Q1/68;G01N33/53;A61K38/00;A61P11/06;A61P35/00;A61P37/08;A61P43/00;C07K16/00;C07K16/18;C07K16/22;C07K16/28;C07K16/42;C12N1/15;C12N1/19;C12N1/21;C12N5/02;C12N5/10;C12N5/16;C12N15/09;C12N15/13;C12P21/02;C12P21/06;G01N33/566 |
主分类号 |
C12Q1/68 |
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