| 发明名称 |
Aminopyrimidine compounds and methods of use |
| 摘要 |
The invention relates to aminopyrimidine compounds useful for treating diseases mediated by polo-like kinase 1 (Plk1). The invention also relates to the therapeutic use of such aminopyrimidine compounds and compositions thereof in treating disease states associated with abnormal cell growth and unwanted cell proliferation.
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| 申请公布号 |
US7786132(B2) |
申请公布日期 |
2010.08.31 |
| 申请号 |
US20050304901 |
申请日期 |
2005.12.16 |
| 申请人 |
AMGEN INC. |
发明人 |
SMITH ADRIAN LEONARD;BRENNAN PAUL EDWARD;DEMORIN FRENEL FILS;LIU GANG;PARAS NICK A.;RETZ DANIEL MARTIN;RAINBEAU ELIZABETH |
| 分类号 |
C07D409/14;A61K31/506;A61P19/02;A61P35/00;C07D417/14 |
主分类号 |
C07D409/14 |
| 代理机构 |
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