发明名称 |
Gastric acid secretion inhibiting composition |
摘要 |
An oral pharmaceutical dosage form comprises pharmacologically effective amounts of an acid-susceptible proton pump inhibitor and an H2 receptor antagonist in combination with at least on pharmacologically acceptable excipient which causes a delayed release and/or an extended release of the proton pump inhibitor. The H2 receptor antagonist is included in the dosage form in such a way that it is rapidly released after administration. This dosage form is suitable for the treatment of conditions associated with an excessive secretion of gastric acid and provides a suitable combination of a rapid onset and a long-lasting duration of the effect. The invention also relates to a method for manufacturing such a dosage form and to a method for the treatment of conditions associated with the secretion of gastric acid.
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申请公布号 |
US7785626(B2) |
申请公布日期 |
2010.08.31 |
申请号 |
US20050531598 |
申请日期 |
2005.11.25 |
申请人 |
OREXO AB |
发明人 |
PETTERSSON ANDERS;NYSTROEM CHRISTER;HAAKANSSON YVONNE |
分类号 |
A61K9/24;A61K9/00;A61K9/16;A61K9/20;A61K9/48;A61K9/50;A61K31/341;A61K31/4164;A61K31/426;A61K31/4439;A61K45/06;A61P1/04 |
主分类号 |
A61K9/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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