Compounds that inhibit the binding of the Smac protein to Inhibitor of Apoptosis Proteins (IAPs) of the formula (IVa). Compounds of formula IVa are useful for the treatment of proliferative diseases, including cancer.
申请公布号
NZ549925(A)
申请公布日期
2010.08.27
申请号
NZ20050549925
申请日期
2005.04.06
申请人
NOVARTIS AG
发明人
PALMERO, MARK G;SHARMA, SUSHIL KUMAR;STRAUB, CHRISTOPHER;WANG, RUN-MING;ZAWEL, LEIGH;ZHANG, YANLIN;CHEN, ZHUOLIANG;WANG, YAPING;YANG, FAN;WRONA, WOJCIECH;LIU, GANG;CHAREST, MARK G;HE, FENG