发明名称 Polymorphic and amorphous forms of the phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one
摘要 Disclosed is a crystalline phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one (the pictured formula), wherein the salt is one of six substantially pure polymorph with X-ray powder diffraction patterns as described in the specification. Also disclosed is the use of the salt for treating cancer.
申请公布号 NZ554659(A) 申请公布日期 2010.08.27
申请号 NZ20050554659 申请日期 2005.09.12
申请人 PFIZER INC.;CANCER RESEARCH TECHNOLOGY LTD. 发明人 LIU, JIA;NAYYAR, NARESH;GUO, MING;WU, ZHEN-PING;BORER, BENNETT CHAPLIN;SRIRANGAM, APARNA NADIG;MITCHELL, MARY BRYAN;LI, YI;CHU, JAN-JON
分类号 C07D487/06;A61K31/55;A61P25/00;A61P35/00 主分类号 C07D487/06
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