发明名称 |
Polymorphic and amorphous forms of the phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one |
摘要 |
Disclosed is a crystalline phosphate salt of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one (the pictured formula), wherein the salt is one of six substantially pure polymorph with X-ray powder diffraction patterns as described in the specification. Also disclosed is the use of the salt for treating cancer.
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申请公布号 |
NZ554659(A) |
申请公布日期 |
2010.08.27 |
申请号 |
NZ20050554659 |
申请日期 |
2005.09.12 |
申请人 |
PFIZER INC.;CANCER RESEARCH TECHNOLOGY LTD. |
发明人 |
LIU, JIA;NAYYAR, NARESH;GUO, MING;WU, ZHEN-PING;BORER, BENNETT CHAPLIN;SRIRANGAM, APARNA NADIG;MITCHELL, MARY BRYAN;LI, YI;CHU, JAN-JON |
分类号 |
C07D487/06;A61K31/55;A61P25/00;A61P35/00 |
主分类号 |
C07D487/06 |
代理机构 |
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