| 摘要 |
Disclosed is a composition comprising two biocompatible organic solvents, a polar lipid, at least one or more surfactant, wherein said surfactant comprises a docusate, 40-65 % by weight of water, urea and thickener; wherein the organic solvents comprise an ester and propylene glycol; and wherein the composition comprises 2 to 30% by weight of the ester and 0.5 to 20% by weight of the propylene glycol, and wherein said ester is an isopropyl ester of a fatty acid having 4 to 22 carbon atoms. Also disclosed is a method of making the above composition, and the use of the composition to deliver a medicament topically into and through the epidermis tissue, such as to treat skin or nail infections or diseases.
|
