发明名称 |
METHOD FOR IMPROVING CARTILAGE REPAIR AND/OR PREVENTING CARTILAGE DEGENERATION IN A JOINT |
摘要 |
The invention is in the field of methods for medical treatment. It provides an improved method for repairing damaged cartilage and/or preventing cartilage degeneration in tissue, in particular in a joint by administering a pharmaceutically active agent directly into the fat pad of a joint. The pharmaceutically active agent is preferably selected from the group consisting of agents that stimulate chondrogenic differentiation and/or cartilage matrix synthesis; agents that inhibit osteogenesis and/or hypertrophy, anti-inflammatory agents, agents that inhibit apoptosis of chondrocytes, agents that inhibit senescence of chondrocytes and agents that enhance lubrication of a joint.
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申请公布号 |
US2010215731(A1) |
申请公布日期 |
2010.08.26 |
申请号 |
US20100709169 |
申请日期 |
2010.02.19 |
申请人 |
MAASTRICHT UNIVERSITY;ACADEMIC HOSPITAL MAASTRICHT |
发明人 |
EMANS PETER JOSEPH;VAN RHIJN LODEWIJK WILLEM;WELTING TIM JOHANNES MARIA;DE LEEUW MIKE |
分类号 |
A61K38/19;A61K9/00;A61K9/127;A61K31/42;A61K31/728;A61K38/02;A61K38/17;A61K38/39;A61K38/45;A61K39/395;A61P19/00;A61P19/02;A61P19/10 |
主分类号 |
A61K38/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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