摘要 |
<p>Disclosed is a compound represented by formula (I) or a salt thereof, which has GPR 119 agonist action and excellent medicinal effects useful for prevention/treatment of diabetes, adiposis and the like. In the formula, P represents a substituted 6-membered aromatic ring; Q represents a (substituted) 6-membered aromatic ring; A1 represents CR4aR4b, NR4c, O, S, SO, SO2 (wherein R4a-R4c each represents H or the like); L1 represents a (substituted) C1-5 alkylene; L2 represents a bond, a (substituted) C1-3 alkylene; L3 and L4 each represents a (substituted) C1-3 alkylene; R1 represents H, X, CN, a (substituted) hydrocarbon, a (substituted) heterocyclic ring or a (substituted) OH, or alternatively combines with A1 to form a (substituted) 4- to 8-membered (heterocyclic) ring; R2 represents H, CN or a (substituted) hydrocarbon; and R3a represents -COSRA1 or a (substituted) 5- or 6-membered aromatic ring (wherein RA1 represents a (substituted) hydrocarbon or a (substituted) heterocyclic ring).)</p> |
申请人 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED;RIKIMARU, KENTARO;IMOTO, HIROSHI;KAMAURA, MASAHIRO |
发明人 |
RIKIMARU, KENTARO;IMOTO, HIROSHI;KAMAURA, MASAHIRO |