发明名称 |
Use of Quinazoline Derivative ZD6474 Combined With Platinum Compounds and Optionally Ionising Radiation in the Treatment of Diseases Associated With Angiogenesis and/or Increased Vascular Permeability |
摘要 |
The present invention relates to a method for the production of an antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation, particularly a method for the treatment of a cancer, particularly a cancer involving a solid tumour, which comprises the administration of ZD6474 in combination with a platinum anti-tumour agent; to a pharmaceutical composition comprising ZD6474 and a platinum anti-tumour agent; to a combination product comprising ZD6474 and a platinum anti-tumour agent for use in a method of treatment of a human or animal body by therapy; to a kit comprising ZD6474 and a platinum anti-tumour agent; to the use of ZD6474 and a platinum anti-tumour agent in the manufacture of a medicament for use in the production of all antiangiogenic and/or vascular permeability reducing effect in a warm-blooded animal such as a human which is optionally being treated with ionising radiation.
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申请公布号 |
US2010215773(A1) |
申请公布日期 |
2010.08.26 |
申请号 |
US20090624760 |
申请日期 |
2009.11.24 |
申请人 |
ASTRAZENECA AB |
发明人 |
WEDGE STEPHEN ROBERT;RYAN ANDERSON JOSEPH |
分类号 |
A61K33/24;A61K31/282;A61K31/517;A61K31/555;A61K41/00;A61P35/00 |
主分类号 |
A61K33/24 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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