发明名称 ACID ADDITION SALT OF UDENAFIL, PREPARATION METHOD THEREOF AND PHAMACEUTICAL COMPOSITION COMPRISING THE SAME
摘要 The present invention provides an acid addition salt of Udenafil, a preparation method thereof and a pharmaceutical composition comprising the same. The acid addition salt of Udenafil in which Udenafil is bonded to an organic acid selected from the group consisting of oxalic acid, benzenesulfonic acid, camphorsulfonic acid, cinnamic acid, adipic acid and cyclamic acid, has excellent solubility in an aqueous medium, water stability and crystallinity, thereby being suitably applied for a pharmaceutical composition.
申请公布号 CA2751639(A1) 申请公布日期 2010.08.26
申请号 CA20102751639 申请日期 2010.02.17
申请人 DONG-A PHARM., CO., LTD. 发明人 LEE, CHAN-HO;SHIN, CHANG-YONG;CHOI, SEUL-MIN;KANG, KYUNG-KOO;KIM, DONG-SEONG;AHN, BYOUNG-OK;YOO, MOO-HI
分类号 C07D487/04;C07D487/02 主分类号 C07D487/04
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