发明名称 |
Sirtuin modulating compounds |
摘要 |
Provided herein are novel sirtuin-modulating compounds and methods of use thereof. The sirtuin-modulating compounds may be used for increasing the lifespan of a cell, and treating and/or preventing a wide variety of diseases and disorders including, for example, diseases or disorders related to aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting disorders, inflammation, cancer, and/or flushing as well as diseases or disorders that would benefit from increased mitochondrial activity. Also provided are compositions comprising a sirtuin-modulating compound in combination with another therapeutic agent. |
申请公布号 |
ZA200908883(B) |
申请公布日期 |
2010.08.25 |
申请号 |
ZA20090008883 |
申请日期 |
2009.12.14 |
申请人 |
SIRTRIS PHARMACEUTICALS, INC. |
发明人 |
BEMIS, JEAN;DISCH, JEREMY, S;NG, PUI, YEE;OALMANN, CHRISTOPHER;PERNI, ROBERT, B;VU, CHI, B |
分类号 |
A61K;A61P;C07D |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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