发明名称 |
C-glycolipids with enhanced TH-1 profile |
摘要 |
The invention is directed to novel synthetic C-glycolipids that selectively induce a ThI-type immune response characterized by enhanced IL-12 secretion and increased activation of dendritic cells. The compounds of the invention are thereby useful in treating infections, cancers, cell proliferative disorders, and autoimmune diseases, both directly and as adjuvants. |
申请公布号 |
ZA200810710(B) |
申请公布日期 |
2010.08.25 |
申请号 |
ZA20080010710 |
申请日期 |
2008.12.19 |
申请人 |
NEW YORK UNIVERSITY;RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEWYORK;THE AARON DIAMOND AIDS RESEARCH CENTER FOR THE CITY OF NEW YORK, INC. |
发明人 |
TSUJI, MORIYA;CHEN, GUANGWU;FRANCK, RICHARD;YANG, GUANGLI |
分类号 |
A61K |
主分类号 |
A61K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|