发明名称 |
PROTEIN-RESPONSIVE TRANSLATION CONTROL SYSTEM UTILIZING RNA-PROTEIN INTERACTION MOTIF |
摘要 |
An object of the present invention is to provide a translationally regulatable mRNA which has wider application and can perform specific ON-OFF regulation, an RNA-protein complex specifically bound to the mRNA, and a translational regulatory system. The present invention provides an mRNA having an RNA-protein complex interacting motif-derived nucleotide sequence 5' to the ribosome-binding site or within the 5' region of the open reading frame, and an mRNA having a nucleotide sequence complementary to an RNA-protein complex interacting motif-derived nucleotide sequence 5' to the ribosome-binding site or within the 5' region of the open reading frame. |
申请公布号 |
EP2221367(A1) |
申请公布日期 |
2010.08.25 |
申请号 |
EP20080851746 |
申请日期 |
2008.11.21 |
申请人 |
JAPAN SCIENCE AND TECHNOLOGY AGENCY |
发明人 |
INOUE, TAN;SAITO, HIROHIDE;KOBAYASHI, TETSUHIRO;HARA, TOMOAKI |
分类号 |
C12N15/00;C07K14/435;C12N15/09;C12N15/67;C12P21/02 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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