发明名称 PEGylated single domain antibodies (dAb)
摘要 Disclosed is a PEG-linked polypeptide comprising an antibody single variable domain, wherein the variable domain comprises a framework region and has an antigen binding site, and said variable domain binds antigen as a single antibody variable domain in the polypeptide, and further wherein said PEG is present as one or more molecules linked to the polypeptide at a cysteine or lysine residue in the framework regions of said antibody single variable domain.
申请公布号 EP2221317(A2) 申请公布日期 2010.08.25
申请号 EP20080166692 申请日期 2004.06.30
申请人 DOMANTIS LIMITED 发明人 BASRAN, AMRIK
分类号 C07K16/46;A61K47/48;C07K16/00;C07K16/18;C07K16/24;C07K16/28;C07K16/40;C12N5/10;C12N15/13;C12N15/79;G01N33/542;G01N33/577;G01N33/68 主分类号 C07K16/46
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