发明名称 |
MEANS AND METHODS FOR TREATING OR PREVENTING BRAIN TUMORS BASED ON THE NUCLEAR RECEPTOR TAILLESS (TLX) |
摘要 |
The present invention relates to the use of an inhibitor of tailless gene expression or tailless protein activity for the preparation of a pharmaceutical composition for treating or preventing the brain tumor in a subject. Preferably an inhibitor of tailless expression is a single or double stranded RNA. An inhibitor of tailless protein activity is preferably an antibody which specifically binds thereto. Finally, the invention includes methods for identifying anti-brain tumor drugs. |
申请公布号 |
EP2219628(A1) |
申请公布日期 |
2010.08.25 |
申请号 |
EP20080854479 |
申请日期 |
2008.11.18 |
申请人 |
DKFZ DEUTSCHES KREBSFORSCHUNGSZENTRUM, STIFTUNG DES OEFFENTLICHEN RECHTS |
发明人 |
LIU, HAI-KUN;SCHUETZ, GUENTHER |
分类号 |
A61K31/00;C07K14/705;C07K16/00;C12N15/113 |
主分类号 |
A61K31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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