摘要 |
Provided herein are Heteroaryl Compounds having the following structure:
wherein R 1 , R 2 , L, X, Y, Z, Q, A and B are as defined herein, compositions comprising an effective amount of a Heteroaryl Compound and methods for treating or preventing cancer, inflammatory conditions, immunological conditions, metabolic conditions and conditions treatable or preventable by inhibition of a kinase pathway comprising administering an effective amount of a Heteroaryl Compound to a patient in need thereof. |
申请人 |
SIGNAL PHARMACEUTICALS, LLC. |
发明人 |
MORTENSEN, DEBORAH SUE;MEDEROS, MARIA MERCEDES DELGADO;SAPIENZA, JOHN JOSEPH;ALBERS, RONALD J;LEE, BRANDEN G;HARRIS, ROY LEONARD, III;SHEVLIN, GRAZIELLA ISABEL;HUANG, DEHUA;SCHWARZ, KIMBERLY LYN;PACKARD, GARRICK K;PARNES, JASON SIMON;PAPA, PATRICK WILLIAM;TEHRANI, LIDA RADNIA;PERRIN-NINKOVIC, SOPHIE;RIGGS, JENNIFER R |