发明名称 6-Phenyl-1H-Imidazo[4,5-C]Pyridine-4-Carbonitrile derivatives as cathepsin inhibitors
摘要 The present invention relates to 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives having the general Formula (I), to pharmaceutical compositions comprising the same as well as to the use of these derivatives for the preparation of a medicament for the treatment of cathepsin S related diseases such asatherosclerosis,obesity, inflammation and immune disorders, such as rheumatoid arthritis, psoriasis, cancer,and chronic pain, such as neuropathic pain.
申请公布号 ZA200909132(B) 申请公布日期 2010.08.25
申请号 ZA20090009132 申请日期 2009.12.21
申请人 N.V. ORGANON 发明人 CAI, JIAQIANG;RANKOVIC, ZORAN;JONES, PHILIP STEPHEN;BENNETT, DAVID JONATHAN;FRADERA, XAVIER
分类号 A61K;A61P;C07D 主分类号 A61K
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