发明名称 |
PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF BONE FRACTURE |
摘要 |
Disclosed herein is a composition for the treatment bone fracture comprising N-hydroxy-4-{5- [4- (5-isopropyl-2- methyl-1, 3-thiazol-4-yl)phenoxy] pentoxyl -benzamidine, 4-{5- [4- (5-isopropyl-2-methyl--l, 3-thiazol-4-yl)phenoxy]pentoxy}- benzamidine or pharmaceutically acceptable salts thereof as a medicinally effective ingredient. The composition of the present invention can significantly reduce the volume of bony callus, increase bony density and strength of bony callus, and decrease the contents of connective tissue and cartilage tissue in bony callus, and thus promote loss and ossification of the bony callus formed during the fracture healing process. Therefore, the composition of the present invention is useful for the treatment of bone fracture.
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申请公布号 |
CA2572897(C) |
申请公布日期 |
2010.08.24 |
申请号 |
CA20052572897 |
申请日期 |
2005.07.05 |
申请人 |
DONG WHA PHARMACEUTICAL IND. CO., LTD. |
发明人 |
LEE, JIN SOO;KU, SAE KWANG;LEE, JUNG WOO;YANG, HEE BOG;RYU, JEI MAN |
分类号 |
A61K31/426;A61P19/00 |
主分类号 |
A61K31/426 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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