发明名称 Analogs of nitrobenzylthioinosine
摘要 Analogs or derivatives of nitrobenzylthioinosine corresponding to formula I: in which R represents an unsubstituted or mono- or polysubstituted phenyl, benzyl or heteroaryl group or a phenyl group condensed with heteroaryl, and R″ represents an unsubstituted or mono- or polysubstituted NH—C1-6-alkyl, NH-aryl, NH-heteroaryl, NH—C3-8-cycloalkyl, NH—C1-3-alkyl-aryl, NH—C1-3-alkyl-heteroaryl, N(C1-6-alkyl)2, N(C1-3-alkyl-aryl)2, N(C1-3-alkyl-heteroaryl)2, piperidine, piperazine, morpholine or pyrrolidine group; pharmaceutical compositions comprising such analogs or derivatives, and the use of such analogs or derivatives for treating pain and/or various other diseases.
申请公布号 US7781432(B2) 申请公布日期 2010.08.24
申请号 US20060647222 申请日期 2006.12.29
申请人 GRUENENTHAL GMBH;LEIDEN UNIVERSITY 发明人 IJZERMANN ADRIAAN PIETER;TROMP REYNIER
分类号 C07D473/24;A61K31/52;A61P25/04 主分类号 C07D473/24
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