| 发明名称 |
O-methylated rapamycin derivatives for alleviation and inhibition of lymphoproliferative disorders |
| 摘要 |
The present invention relates to methods of alleviating and inhibiting a lymphoproliferative disorder in a mammal, the method comprising administering one or more rapamycin derivatives (including rapamycin) to the mammal. Further, the invention provides a method for identifying agents which are useful for alleviating and inhibiting a lymphoproliferative disorders, as well as a method for identifying agents which are capable of inhibiting metastasis of lymphatic tumors in a mammal.
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| 申请公布号 |
US7781447(B2) |
申请公布日期 |
2010.08.24 |
| 申请号 |
US20070899673 |
申请日期 |
2007.09.07 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA |
发明人 |
WASIK MARIUSZ A.;SHAW LESLIE M. |
| 分类号 |
A01N43/42;C07D498/18;A61K31/343;A61K31/42;A61K31/436;A61K31/44;A61K31/445;A61K31/4745;A61K31/52;A61K31/664;A61K33/24;A61K38/00;A61K39/395;A61K45/00;A61P35/00;A61P35/02;A61P37/06;G01N33/50 |
主分类号 |
A01N43/42 |
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