发明名称 |
COMPOSITIONS AND METHODS FOR REDUCING RESPIRATORY DEPRESSION |
摘要 |
The present invention relates to diarylmethyl piperazine compounds and diarylmethyl piperidine compounds, and pharmaceutical compositions thereof, having utility in medical therapy especially for reducing respiratory depression associated with certain analgesics, such as mu opiates. This invention additionally relates to diarylmethyl piperazine compounds and diarylmethyl piperidine compounds having utility in assays for determining the respiratory reducing characteristics of other bioactive compounds, including other diarylmethyl piperazine compounds and other diarylmethyl piperidine compounds.
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申请公布号 |
CA2257393(C) |
申请公布日期 |
2010.08.24 |
申请号 |
CA19972257393 |
申请日期 |
1997.05.28 |
申请人 |
DELTA PHARMACEUTICALS, INC. |
发明人 |
CHANG, KWEN-JEN;MCNUTT, ROBERT W., JR.;PETTIT, HUGH O.;BISHOP, MICHAEL J. |
分类号 |
A61K31/496;A61K31/00;A61K31/445;A61K31/495;C07D295/096;C07D295/155 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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