COMPOSITION FOR PREVENTING AND TREATING INFLAMMATORY KIDNEY DISEASE COMPRISING GENISTEIN

摘要

PURPOSE: A composition containing genistein for preventing and treating inflammatory renal diseases is provided to suppress inflammatory renal diseases including acute renal injury. CONSTITUTION: A composition for preventing and treating inflammatory renal disease contains genistein. The disease is a disease cause by anticancer drug administration. The anticancer drug is cisplatin(cis-Diamminedichloroplatinum). Genistein reduces ICAM-1 and MCP-1 expression and suppresses NF-kappaB activation and ROS generation.