| 发明名称 |
CYCLOALKYL INHIBITOR OF POTASSIUM CHANNEL FUNCTION |
| 摘要 |
PROBLEM TO BE SOLVED: To develop new inhibitors of potassium channel function (especially inhibitors of the K<SB>v</SB>1 subfamily of voltage gated K<SP>+</SP>channels, especially inhibitors K<SB>v</SB>1.5 which have been linked to the ultra-rapidly activating delayed rectifier K<SP>+</SP>current I<SB>Kur</SB>). SOLUTION: The present invention relates to new cycloalkyl compounds, methods of using such compounds in the prevention and treatment of arrythmia and I<SB>Kur</SB>-associated conditions, and pharmaceutical compositions containing such compounds. COPYRIGHT: (C)2010,JPO&INPIT
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| 申请公布号 |
JP2010180208(A) |
申请公布日期 |
2010.08.19 |
| 申请号 |
JP20100032357 |
申请日期 |
2010.02.17 |
| 申请人 |
BRISTOL MYERS SQUIBB CO;ICAGEN INC |
发明人 |
JOHN LLOYD;JEON YOON T;FINLAY HEATHER;YANG LING;GROSS MICHAEL F;BEAUDOIN SERGE |
| 分类号 |
C07C307/08;A61K;A61K31/16;A61K31/166;A61K31/18;A61K31/277;A61K31/341;A61K31/343;A61K31/351;A61K31/36;A61K31/381;A61K31/40;A61K31/401;A61K31/415;A61K31/416;A61K31/4166;A61K31/4192;A61K31/42;A61K31/422;A61K31/4245;A61K31/428;A61K31/433;A61K31/437;A61K31/4375;A61K31/44;A61K31/4406;A61K31/4409;A61K31/4436;A61K31/4439;A61K31/4465;A61K31/455;A61K31/47;A61K31/472;A61K31/496;A61K31/50;A61K31/5375;A61K31/549;A61K31/609;A61K45/06;A61P1/04;A61P3/10;A61P9/00;A61P11/00;A61P11/06;A61P19/02;A61P21/00;A61P25/00;A61P27/02;A61P29/00;A61P35/00;A61P37/02;A61P43/00;C07C233/58;C07C233/59;C07C233/60;C07C233/65;C07C235/06;C07C235/34;C07C235/46;C07C235/60;C07C279/16;C07C279/24;C07C279/28;C07C307/02;C07C307/04;C07C307/06;C07C307/10;C07C311/16;C07C311/29;C07C311/55;C07C311/59;C07C311/64;C07C323/62;C07D207/09;C07D207/16;C07D207/22;C07D207/28;C07D207/327;C07D207/48;C07D209/08;C07D211/62;C07D211/96;C07D213/36;C07D213/40;C07D213/42;C07D213/56;C07D213/69;C07D213/74;C07D213/76;C07D213/81;C07D213/82;C07D213/89;C07D215/48;C07D217/22;C07D217/24;C07D231/14;C07D231/22;C07D231/38;C07D231/56;C07D233/34;C07D233/48;C07D233/54;C07D233/61;C07D233/64;C07D233/72;C07D233/74;C07D233/76;C07D233/78;C07D235/02;C07D235/06;C07D235/08;C07D235/10;C07D235/14;C07D237/24;C07D239/42;C07D239/48;C07D239/91;C07D239/94;C07D239/95;C07D241/06;C07D241/12;C07D241/20;C07D241/24;C07D243/08;C07D249/04;C07D249/06;C07D249/14;C07D251/44;C07D251/46;C07D251/50;C07D257/06;C07D261/08;C07D261/14;C07D261/18;C07D263/26;C07D265/30;C07D271/06;C07D277/62;C07D285/06;C07D285/12;C07D285/135;C07D285/14;C07D285/28;C07D295/12;C07D295/13;C07D295/18;C07D295/185;C07D295/215;C07D295/22;C07D295/26;C07D307/14;C07D307/33;C07D307/52;C07D307/54;C07D307/68;C07D307/79;C07D309/04;C07D309/08;C07D309/20;C07D309/38;C07D317/58;C07D317/68;C07D333/20;C07D333/24;C07D333/28;C07D333/34;C07D333/38;C07D333/58;C07D333/62;C07D403/06;C07D409/12;C07D413/12;C07D471/04;C07D487/04;C07D521/00 |
主分类号 |
C07C307/08 |
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