发明名称 |
Methods of Treatment of Opioid Tolerance, Physical Dependence, Pain and Addiction With Inhibitors of Certain Growth Factor Receptors |
摘要 |
Methods of preventing the development and reversing or partially reversing opioid tolerance in a subject are provided herein. Such methods include the step of administering to a subject in need thereof a therapeutically effective amount of a PDGFR modulator or EGFR modulator alone or together with an opiate analgesic. The methods can also be used for the treatment of refractory neuropathic pain, physical dependence or addiction. |
申请公布号 |
US2010210709(A1) |
申请公布日期 |
2010.08.19 |
申请号 |
US20080682064 |
申请日期 |
2008.10.08 |
申请人 |
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发明人 |
HOWARD GUTSTEIN B. |
分类号 |
A61K31/713;A61K31/506;A61K31/517;A61K31/5377;A61P25/30;A61P29/00 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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