METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER
摘要
The invention relates to compositions comprising an acid ceramidase inhibitor and a choline kinase inhibitor as well as to the uses thereof for the treatment of cancer. The invention also relates to methods for the selection of an individualised therapy of a cancer patient based on the detection of the acid ceramidase levels. Moreover, the invention also relates to compositions comprising a choline kinase inhibitor and a chemotherapeutic agent and uses thereof for the treatment of cancer. Finally, the invention also relates to compositions comprising a choline kinase inhibitor and a death receptor ligand and uses thereof for the treatment of cancer.
申请公布号
WO2010031825(A3)
申请公布日期
2010.08.19
申请号
WO2009EP62078
申请日期
2009.09.17
申请人
TRANSLATIONAL CANCER DRUGS PHARMA, S.L.;RAMIREZ DE MOLINA, ANA;GARCIA OROZ, LOURDES;LACAL SANJUAN, JUAN CARLOS
发明人
RAMIREZ DE MOLINA, ANA;GARCIA OROZ, LOURDES;LACAL SANJUAN, JUAN CARLOS