发明名称 |
ANTI-MST1R ANTIBODIES AND USES THEREOF |
摘要 |
The present disclosure provides recombinant antigen-binding regions and antibodies and functional fragments containing such antigen-binding regions that are specific for MST1R, which plays an integral role in various disorders or conditions, such as cancer. These antibodies, accordingly, can be used to treat these and other disorders and conditions. Antibodies of the disclosure also can be used in the diagnostics field, as well as for further investigating the role of MST1R in the progression of disorders associated with tumors. The disclosure also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use. |
申请公布号 |
CA2752136(A1) |
申请公布日期 |
2010.08.19 |
申请号 |
CA20102752136 |
申请日期 |
2010.02.10 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
KAWAIDA, REIMI;OHTSUKA, TOSHIAKI;AGATSUMA, TOSHINORI;RODLEY, PHILIP;MILLER, SANDRA;SCHUBERT, ULRIKE |
分类号 |
C12N15/13;A61K39/00;A61K39/395;A61P35/00;C07K16/28;C07K16/46;C12N15/85;G01N33/574 |
主分类号 |
C12N15/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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