发明名称 |
THERAPEUTIC AGENT FOR URINARY BLADDER CANCER |
摘要 |
PROBLEM TO BE SOLVED: To provide a therapeutic agent for urinary bladder cancer which is a titanium oxide-antibody complex imparted with a selective binding ability without losing dispersibility and catalytic activity by modifying an antibody through a linker molecule binding a water-soluble polymer to a titanium oxide complex dispersed in an aqueous solvent with the water-soluble polymer without deteriorating the water-soluble polymer. SOLUTION: The therapeutic agent for the urinary bladder cancer includes: the titanium oxide complex having the water-soluble polymer bound through at least one functional group selected from the group consisting of carboxy, amino, diol, salicylic acid, and phosphoric acid to the surface of titanium oxide particles; the linker molecule bound to the surface thereof; and the antibody bound through the linker molecule. COPYRIGHT: (C)2010,JPO&INPIT
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申请公布号 |
JP2010180192(A) |
申请公布日期 |
2010.08.19 |
申请号 |
JP20090027692 |
申请日期 |
2009.02.09 |
申请人 |
TOTO LTD;NATIONAL CANCER CENTER-JAPAN |
发明人 |
KANEHIRA YUKITERU;SONEZAKI SHUJI;OGAMI ARIYOSHI;NAKAMURA TOMOMI;MATSUMURA YASUHIRO |
分类号 |
A61K41/00;A61K9/16;A61K39/395;A61K47/10;A61K47/12;A61K47/18;A61K47/32;A61K47/34;A61K47/42;A61K47/48;A61K49/00;A61P13/10;A61P35/00 |
主分类号 |
A61K41/00 |
代理机构 |
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