发明名称 THERAPEUTIC AGENT FOR URINARY BLADDER CANCER
摘要 PROBLEM TO BE SOLVED: To provide a therapeutic agent for urinary bladder cancer which is a titanium oxide-antibody complex imparted with a selective binding ability without losing dispersibility and catalytic activity by modifying an antibody through a linker molecule binding a water-soluble polymer to a titanium oxide complex dispersed in an aqueous solvent with the water-soluble polymer without deteriorating the water-soluble polymer. SOLUTION: The therapeutic agent for the urinary bladder cancer includes: the titanium oxide complex having the water-soluble polymer bound through at least one functional group selected from the group consisting of carboxy, amino, diol, salicylic acid, and phosphoric acid to the surface of titanium oxide particles; the linker molecule bound to the surface thereof; and the antibody bound through the linker molecule. COPYRIGHT: (C)2010,JPO&INPIT
申请公布号 JP2010180192(A) 申请公布日期 2010.08.19
申请号 JP20090027692 申请日期 2009.02.09
申请人 TOTO LTD;NATIONAL CANCER CENTER-JAPAN 发明人 KANEHIRA YUKITERU;SONEZAKI SHUJI;OGAMI ARIYOSHI;NAKAMURA TOMOMI;MATSUMURA YASUHIRO
分类号 A61K41/00;A61K9/16;A61K39/395;A61K47/10;A61K47/12;A61K47/18;A61K47/32;A61K47/34;A61K47/42;A61K47/48;A61K49/00;A61P13/10;A61P35/00 主分类号 A61K41/00
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