| 摘要 |
The present invention in one aspect related to a ligand binding site for laminin, particularly those laminins comprising an α5 chain. The invention also encompasses binding sites on Lutheran glycoprotein (“Lu gp”) for binding laminin (“LM”) isoforms containing an α5 chain, mutant Lu gp molecules impaired at this binding site, antagonists and enhancers of the site, methods for identifying antagonists and enhancers, and uses of these molecules.
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