发明名称 PROCESSES FOR PRODUCING PHENYL-6-(1-(PHENYL)UREIDO)NICOTINAMIDES)
摘要 The present invention relates to processes for the preparation of compounds useful as inhibitors of p38 kinase. The processes of the present invention are amenable for large scale preparation and produce stable phenyl-6-(l-(phenyl)ureido)nicotinamides in high purity and yields.
申请公布号 WO2010093890(A2) 申请公布日期 2010.08.19
申请号 WO2010US24054 申请日期 2010.02.12
申请人 VERTEX PHARMACEUTICALS INCORPORATED;ROEPER, STEFANIE;LOOKER, ADAM, R.;MARTINOT, THEODORE, A.;NEUBERT-LANGILLE, BOBBIANNA;RYAN, MICHAEL, P.;SNOONIAN, JOHN, R. 发明人 ROEPER, STEFANIE;LOOKER, ADAM, R.;MARTINOT, THEODORE, A.;NEUBERT-LANGILLE, BOBBIANNA;RYAN, MICHAEL, P.;SNOONIAN, JOHN, R.
分类号 C07D213/80;A61K31/4418;A61P29/00;A61P37/06;C07D213/803 主分类号 C07D213/80
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