摘要 |
<P>PROBLEM TO BE SOLVED: To provide a sustained release histocompatible implant suitable to deliver a therapeutic substance of a low payload to a specified region and/or for a long time (it can be several months or several years). <P>SOLUTION: A porous silicon implant 60 impregnated with an efffective substance, such as a micromineral required for healthy physiology, is implanted subcutaneously and is entirely corroded away over the following months/year to release the micromineral in a controlled manner. In a second embodiment, the implant 62 may have a large number of holes 72 which contain effective substance and which are closed by bio-errodable doors 76, 78 of different thickness so as to stagger the release of the effective substance over time as the doors are breached. <P>COPYRIGHT: (C)2010,JPO&INPIT |