| 发明名称 |
METHODS FOR IDENTIFYING THERAPEUTIC AGENTS MODULATING ACTIVITY OF THE IGF2 REPRESSOR ZBED6 |
| 摘要 |
<p>The present invention relates to methods for identifying therapeutic agents capable of modulating the activity of the IGF2 repressor ZBED6 for use in growth promotion,wound healing, angiogenesis, inhibition of muscle wasting, and treatment of cancer,tumours and other malignancies, muscle atrophy, muscle dystrophy, neuropathy,osteoporosis, cachexia, diabetes, obesity, acromegaly, polycystic ovary syndrome, and retinopathy.</p> |
| 申请公布号 |
WO2010093322(A1) |
申请公布日期 |
2010.08.19 |
| 申请号 |
WO2010SE50161 |
申请日期 |
2010.02.11 |
| 申请人 |
ANDERSSON, LEIF BERTIL;ANDERSSON, GOERAN;HJAELM, GOERAN;LINDBLAD-TOH, KERSTIN;CARR, STEVEN A.;JAFFE, JACOB D.;GNIRKE, ANDREAS;MIKKELSEN, TARJEI S |
发明人 |
ANDERSSON, LEIF BERTIL;ANDERSSON, GOERAN;HJAELM, GOERAN;LINDBLAD-TOH, KERSTIN;CARR, STEVEN A.;JAFFE, JACOB D.;GNIRKE, ANDREAS;MIKKELSEN, TARJEI S |
| 分类号 |
C07K14/65;C07K14/47;A61K38/17;A61K48/00;A61P3/04;A61P21/00;G01N33/68 |
主分类号 |
C07K14/65 |
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