| 发明名称 |
CARBOXAMIDE COMPOUNDS AND THEIR USE |
| 摘要 |
Chemokine receptor antagonists, in particular, compounds of Formula (I) that act as antagonists of the chemokine CCR2 receptor, including pharmaceutical compositions and uses thereof to treat or prevent diseases associated with monocyte accumulation, lymphocyte accumulation or leukocyte accumulation are described herein.
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| 申请公布号 |
US2010210633(A1) |
申请公布日期 |
2010.08.19 |
| 申请号 |
US20070445134 |
申请日期 |
2007.10.12 |
| 申请人 |
EPIX DELAWARE, INC. |
发明人 |
LIN JIAN;CHEN DONGLI;KOERNER STEFFI;MELENDEZ ROSA E.;MOHANTY PRADYUMMA;BEN-ZEEV EFRAT;FICHMAN MERAV;MARANTZ YAEL;BECKER OREN;MCCAULEY DILARA;ORBACH PINI;SAHA ASHIS K.;SHACHAM SHARON;XIE MICHAEL |
| 分类号 |
A61K31/541;A61K31/40;A61K31/445;A61K31/4525;A61K31/453;A61K31/454;A61K31/4545;A61K31/496;A61K31/5377;A61P1/16;A61P3/04;A61P3/10;A61P9/10;A61P13/12;A61P17/06;A61P37/06;C07D207/16;C07D211/62;C07D401/04;C07D401/06;C07D405/06;C07D405/14;C07D413/06;C07D413/10;C07D417/06 |
主分类号 |
A61K31/541 |
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