发明名称 MEANS FOR INHIBITING THE EXPRESSION OF OPA1
摘要 The present invention is related to an siRNA comprising an antisense strand and a sense strand, wherein all or a portion of said antisense strand comprises an antisense duplex region, wherein all or a portion of said sense strand comprises a sense duplex region, wherein said antisense duplex region is at least partially complementary to said sense duplex region, wherein said siRNA comprises a duplex region consisting of said antisense duplex region and said sense duplex region, and wherein: a) said antisense strand comprises SEQ ID NO: 3, 5, 7 or 9; or b) said antisense strand comprises an antisense duplex region, all or a portion of which, is complementary to a portion of SEQ ID NOs: 1, 10, 11, 12, 13, 14, 15 and/or 16.
申请公布号 WO2010091878(A2) 申请公布日期 2010.08.19
申请号 WO2010EP00888 申请日期 2010.02.12
申请人 SILENCE THERAPEUTICS AG;KAUFMANN, JOERG;SANTEL, ANSGAR 发明人 KAUFMANN, JOERG;SANTEL, ANSGAR
分类号 C12N15/113 主分类号 C12N15/113
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