| 摘要 |
The invention relates to an active substance for treating alcohol dependence, a pharmaceutical composition, a medicinal agent and a method for treating dependence on the consumption of products containing ethyl alcohol. An active substance is proposed for treating alcohol dependence in humans and warm-blooded animals, comprising substituted 1H-benzimidazoles of the general formula 1 or the pharmaceutically acceptable salts and/or hydrates thereof, in which W denotes an atom of sulphur or the group S=O; R1 denotes one or more substituents selected from hydrogen, halogen, C1-C4 alkyl, C1-C4 alkyloxy, optionally substituted azaheterocyclyl; R2 denotes hydrogen or optionally substituted C1-C4 alkyl; R3 and R4 independently of one another denote optionally identical substituents selected from hydrogen or optionally substituted C1-C4 alkyl; R5 denotes an alkyl substituent selected from hydrogen, optionally substituted C1-C7 alkyl, optionally substituted aryl, optionally substituted heterocyclyl, C1-C4 alkoxycarbonyl, or optionally substituted aminocarbonyl. |
