发明名称 |
PREVENTIVE/REMEDY FOR RETINAL NERVE DISEASES CONTAINING ALKYL ETHER DERIVATIVES OR SALTS THEREOF |
摘要 |
An alkyl ether derivative represented by the following general formula [1]
or its salt: wherein R 1 and R 2 represent each a substituent such as hydrogen, halogen or alkyl; R 3 represents alkylamino, amino or hydroxyl; the ring A represents a 5- or 6-membered aromatic heterocycle or a benzene ring; m and n are each an integer of from 1 to 6; and p is an integer of from 1 to 3; shows an effect of protecting retinal nerve cells and, therefore, is useful as a preventive and/or a remedy for retinal nerve diseases such as glaucoma, diabetic retinopathy, retinal artery obstruction, retinal venous obstruction, macular degeneration and retinopathy of prematurity. |
申请公布号 |
EP1614419(A4) |
申请公布日期 |
2010.08.18 |
申请号 |
EP20040727697 |
申请日期 |
2004.04.15 |
申请人 |
TOYAMA CHEMICAL CO., LTD. |
发明人 |
KIMURA, TATSUO;IWAKAMI, NOBORU;SAITOH, AKIHITO |
分类号 |
A61K31/397;A61K31/40;A61K31/4025;A61K31/435;A61K31/4525;A61K31/4535;A61P9/10;A61P27/02;C07D205/04;C07D207/10;C07D207/12;C07D211/36;C07D405/12;C07D409/12 |
主分类号 |
A61K31/397 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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