<p>This invention relates to anti-OX40L antibodies and, in particular, to anti-OX40L antibodies and variants thereof that contain a Fc part derived from human origin and do not bind complement factor C1q. These antibodies have new and inventive properties causing a benefit for a patient suffering from inflammatory diseases.</p>
申请公布号
EP2218782(A2)
申请公布日期
2010.08.18
申请号
EP20100155663
申请日期
2005.09.16
申请人
F.HOFFMANN-LA ROCHE AG
发明人
ENDL, JOSEF;GRAUS, YVO;PARREN, PAUL;SEEBER, STEFAN;EUGUI, ELSIE;LABRIJN, ARAN FRANK;REBERS, FRANK;VAN VUGT, MARTINE;FUENTES, MARIA;LANZENDOERFER, MARTIN;SCHUMACHER, RALF;VAN DE WINKEL, JAN