发明名称 |
Quinazoline analogs as receptor tyrosine kinase inhibitors |
摘要 |
This invention concerns quinazoline analogs of Formula I: where an A group is bonded to at least one of the carbons at the 5, 6, 7 or 8 position of the bicyclic ring, and the ring is substituted by up to three independent R3 groups. The invention also includes methods of using these compounds as type I receptor tyrosine kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.
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申请公布号 |
US7777032(B2) |
申请公布日期 |
2010.08.17 |
申请号 |
US20090496973 |
申请日期 |
2009.07.02 |
申请人 |
ARRAY BIOPHARMA INC. |
发明人 |
WALLACE ELI;TOPALOV GEORGE;LYSSIKATOS JOSEPH;BUCKMELTER ALEXANDRE;ZHAO QIAN |
分类号 |
C07D239/00;C07D239/70;C07D239/94;C07D401/12;C07D413/12;C07D413/14;C07D417/14;C07D471/00;C07D487/00;C07D498/04;C07D498/08 |
主分类号 |
C07D239/00 |
代理机构 |
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地址 |
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