| 发明名称 |
Platinum analogs with bis-nitrile-containing ligands |
| 摘要 |
Disclosed herein are novel platinum-based analogs possessing two nitrile substituent groups (bis-nitrile) covalently-bonded to the platinum. Also disclosed herein are the reaction schemes for the synthesis of said platinum complexes, as well as quantitative in vitro IC50 data.
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| 申请公布号 |
US7777060(B2) |
申请公布日期 |
2010.08.17 |
| 申请号 |
US20070978818 |
申请日期 |
2007.10.30 |
| 申请人 |
BIONUMERIK PHARMACEUTICALS, INC. |
发明人 |
CHEN XINGHAI;PETLURU PAVANKUMAR N. V.;HUANG QIULI;NARKUNAN KESAVARAM;HAUSHEER FREDERICK |
| 分类号 |
C07F15/00;A61K31/282;A61P35/00 |
主分类号 |
C07F15/00 |
| 代理机构 |
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