发明名称 Dual-acting antihypertensive agents
摘要 The invention is directed to compounds of formula I: wherein Ar, r, R3, X, and R5-7 are as defined in the specification, and pharmaceutically acceptable salts thereof. The compounds of formula I have AT1 receptor antagonist activity and neprilysin inhibition activity. The invention is also directed to pharmaceutical compositions comprising such compounds; methods of using such compounds; and a process and intermediates for preparing such compounds.
申请公布号 US7777077(B2) 申请公布日期 2010.08.17
申请号 US20080012161 申请日期 2008.01.31
申请人 THERAVANCE, INC. 发明人 CHOI SEOK-KI;FATHEREE PAUL R.;HUDSON RYAN;JENDZA KEITH;MCKINNELL ROBERT M.;SASIKUMAR VIVEK
分类号 C07C239/00;C07D257/00 主分类号 C07C239/00
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