| 发明名称 |
USE OF EP4 RECEPTOR LIGANDS IN THE TREATMENT OF IL-6 INVOLVED DISEASES |
| 摘要 |
The present invention relates to the use of an EP4 receptor ligand in the manufacture of a medicament for the treatment of IL-6 involved diseases. Also relates to the assay comprising: culturing peripheral whole blood with a test compound; and determining the effect of the compound on PGE2-induced whole blood cells activation.
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| 申请公布号 |
CA2481535(C) |
申请公布日期 |
2010.08.17 |
| 申请号 |
CA20032481535 |
申请日期 |
2003.04.03 |
| 申请人 |
PFIZER INC. |
发明人 |
SHIMOJO, MASATO;TANIGUCHI, KANA |
| 分类号 |
A61K31/635;C12Q1/02;A61K31/00;A61K31/403;A61K31/4178;A61K31/4184;A61K31/4188;A61K31/42;A61K31/421;A61K31/422;A61K31/426;A61K31/427;A61K31/433;A61K31/437;A61K31/4439;A61K31/444;A61K31/4709;A61K31/4725;A61K31/4745;A61K31/498;A61K31/502;A61K31/52;A61K31/522;A61K31/53;A61K45/00;A61P1/16;A61P7/02;A61P9/00;A61P9/10;A61P21/00;A61P25/00;A61P25/28;A61P37/06;A61P43/00;C07D235/08;C07D401/04;C07D401/06;C07D401/12;C07D403/04;C07D403/12;C07D417/04;C07D471/04;C07D473/00;C07D491/04;G01N33/80 |
主分类号 |
A61K31/635 |
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