| 发明名称 |
Amido compounds and their use as pharmaceuticals |
| 摘要 |
The present invention relates to inhibitors of 11-&bgr; hydroxyl steroid dehydrogenase type 1, antagonists of the mineralocorticoid receptor (MR), and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of 11-&bgr; hydroxyl steroid dehydrogenase type 1 and/or diseases associated with aldosterone excess.
|
| 申请公布号 |
US7776874(B2) |
申请公布日期 |
2010.08.17 |
| 申请号 |
US20080136529 |
申请日期 |
2008.06.10 |
| 申请人 |
INCYTE CORPORATION |
发明人 |
YAO WENQING;ZHUO JINCONG;XU MEIZHONG;METCALF BRIAN W.;HE CHUNHONG;QIAN DING-QUAN;ZHANG COLIN |
| 分类号 |
A61K31/443;A61K31/34;A61K31/401;A61K31/4025;A61K31/445;C07D207/06;C07D207/08;C07D207/10;C07D207/12;C07D207/14;C07D207/16;C07D207/263;C07D207/30;C07D209/08;C07D209/42;C07D209/44;C07D209/52;C07D209/54;C07D209/62;C07D209/70;C07D211/16;C07D211/18;C07D211/22;C07D211/34;C07D211/46;C07D211/48;C07D211/52;C07D211/58;C07D211/64;C07D211/66;C07D211/70;C07D213/38;C07D213/46;C07D217/06;C07D217/26;C07D221/00;C07D221/20;C07D223/02;C07D223/04;C07D231/04;C07D295/185;C07D333/34;C07D401/04;C07D401/06;C07D401/10;C07D401/14;C07D403/04;C07D405/04;C07D405/14;C07D407/10;C07D413/10;C07D413/14;C07D417/04;C07D471/04;C07D471/10;C07D487/04;C07D487/08;C07D487/10;C07D491/10;C07D491/20;C07D493/10;C07D495/04;C07D498/20;C07D513/10 |
主分类号 |
A61K31/443 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
